ABSTRACT

Unexplained pneumonia cases caused by a new coronavirus known as SARS-COV-2, occurred in Wuhan, China since December 2019. Culprit of the worldwide pandemic of the coronavirus disease 2019 (COVID-19), SARS-CoV-2 attach to the angiotensin-converting enzyme 2 receptor, affecting multiple systems such as respiratory, vascular, renal and central nervous system. Most common neurological symp- toms are headache, dizziness, nausea, vomiting, myalgia, anosmia, ageusia and altered consciousness; however, there are reports that suggests an association between Guillain-Barre syndrome (GBS) and COVID-19 infection. Guillain-Barre syndrome (GBS) is an autoimmune polyradiculoneuropathy that characterized with progressive weakness of the limbs and reduction or loss of tendon reflexes. Protein concentrations of cerebrospinal fluid (CSF) are increased and the white cell count is normal. Plasma exchange and intravenous immunoglobulin (IVIG) used in treatment with supportive care and most of patients have full recovery. In this paper we aimed to present a patient with positive real time polymerase chain reaction (RT- PCR) test presenting to the emergency department (ED) with the symptoms of GBS. Keywords: Guillain-barre, COVID-19, COVID