ABSTRACT

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Anahtar Kelimeler: Abstract: Objective: Keywords: Şehir Tıp Dergisi, 2020; 1(2): 63-66 Abstract: Sheehan’s syndrome is known as pituitary insufficiency that develops after bleeding and hypovolemia at birth or after birth. The pathological and clinical findings of Sheehan’s syndrome were first described by Harold L. Sheehan. Due to improvements in obstetric care, the frequency of the disease has declined worldwide. Sheehan syndrome is a rare cause of hypopituitarism in developed countries. However, it is more common in underdeveloped and developing countries. Small sella size enlargement of the pituitary gland, autoimmunity also play a role in the pathogenesis of the disease. Depending on the pituitary damage, symptoms may appear immediately or years later. It may be presented as isolated hormone deficiency or panhypopituitarism. For diagnosis, it is important to have a history of excessive hemorrhage at birth, amenorrhea, and the inability to breastfeed. Lymphocytic hypophysitis should be remembered in the differential diagnosis. In this review, a patient with severe post-partum hemorrhage, followed by a history of 3 pregnancies, was presented with a slow-developing and pan hypopituitarism-causing Sheehan’s syndrome and current physiopathological data in Sheehan’s syndrome were presented.