ABSTRACT

Introduction

MPI is an echocardiographic parameter that exhibits the left ventricular functions globally. NT-proBNP is an important both diagnostic and prognostic factor in heart failure. In this study, we aimed to investigate the prognostic significance of serum NTproBNP levels and MPI in patients with STEMI.

Method

Totally, 104 patients with a diagnosis of STEMI were included in the study. Patients were followed for 30-days and questioned for the presence of symptoms of heart failure (HF) and cardiac death. Patients were invited for outpatient control after 30-days and were divided into two groups: (HF (+) group) and (HF (-) group).

Results

Totally, 104 patients with STEMI were hospitalized in the coronary intensive care unit. Of those patients, 17 were female (16%), 87 were male (84%), and the mean age of the patients was 58.9±10.8 years. During the 30-day follow-up, 28 (27%) of 104 patients developed HF. The mean age, hypertension ratio, and anterior STEMI rate were significantly higher in the HF (+) group compared to the HF (-) group. Ejection time (ET) and left ventricular ejection fraction (LVEF) were significantly lower, and MPI was significantly higher in the HF (+) group. When the values on day first and sixth were compared, NT-ProBNP levels were decreased in both groups. There was no significant difference between the two groups in terms of the change in MPI values on the first and sixth days. Multiple regression analyses showed that the presence of anterior MI, first-day NT-proBNP level, and LVEF were independently associated with the development of HF and death.

Conclusion

In our study, NT-proBNP levels were found to be positively associated with MPI in patients with acute STEMI. It was concluded that the level of NT-proBNP, especially on the 1st day, was more valuable than MPI in determining HF development and prognosis after STEMI